Effect of sodium fluoride, ampicillin, and chlorhexidine on Streptococcus mutans biofilm detachment.

نویسندگان

  • Jia Liu
  • Jun-Qi Ling
  • Kai Zhang
  • Li-Jun Huo
  • Yang Ning
چکیده

We examined the effect of three clinically used antimicrobials on Streptococcus mutans UA159 biofilm detachment under flow conditions. Sodium fluoride (NaF) and chlorhexidine at MIC levels promoted biofilm detachment and inhibited detachment when concentrations were higher than the MIC and reduced detached-cell viability only at high concentrations. Ampicillin at all concentrations tested inhibited detachment and reduced the percentage of viable biofilm-detached cells. All the three antimicrobial treatments reduced biofilm live/dead cell ratios.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 56 8  شماره 

صفحات  -

تاریخ انتشار 2012